IIT-M researchers develop ML tool for better detection of brain tumours

Researchers at the Indian Institute of Technology (IIT) Madras have developed a Machine Learning (ML)-based computational tool for better detection of cancer-causing tumours in the brain and spinal cord such as Glioblastoma.

Their findings were published in the peer-reviewed journal Briefings in Bioinformatics.

The tool called aGBMDriver’ (GlioBlastoma Mutiforme Drivers), was developed specifically to identify driver mutations and passenger mutations in glioblastoma. The tool is publicly available online.

“We have identified the important amino acid features for identifying cancer-causing mutations and achieved the highest accuracy for distinguishing between driver and neutral mutations,” said Prof. M. Michael Gromiha, Department of Biotechnology at IIT Madras, in a statement.